Christenson Leslie J
Department of Dermatology, Mayo Clinic, Rochester, MN, USA.
Dermatol Nurs. 2004 Dec;16(6):495-8, 505, 523.
Lentigo maligna melanoma is a melanoma in situ on sun-damaged skin. It is a variably brown-pigmented flat patch on the head or neck of elderly patients. Its growth is generally slow, but it can become an invasive form of melanoma. Multiple reported treatment options are reviewed. Wide-margin Mohs micrographic surgery with peripheral permanent pathologic confirmation of a clear margin is recommended as treatment of choice.
恶性雀斑样痣黑色素瘤是一种发生于受阳光损伤皮肤的原位黑色素瘤。它是老年患者头颈部出现的一种颜色深浅不一的褐色扁平斑片。其生长通常较为缓慢,但可能会发展为侵袭性黑色素瘤。本文综述了多种已报道的治疗方案。推荐采用带广泛切缘的莫氏显微外科手术,并对切缘进行外周永久病理检查以确认切缘阴性,作为首选治疗方法。