Vanacore N, Suzzareddu G, Maggini M, Casula A, Capelli P, Raschetti R
National Centre of Epidemiology, National Institute of Health, Rome, Italy.
Acta Neurol Scand. 2005 Mar;111(3):199-201. doi: 10.1111/j.1600-0404.2005.00388.x.
Three Alzheimer's disease patients with Pisa syndrome were presented. These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study. The clinical and pharmacological histories of these patients suggest a relation between cholinesterase inhibitors and the pleurothotonus. The diffuse use of cholinesterase inhibitors in the treatment of dementia may cause an increasing number of Pisa syndrome cases.
报告了3例患有匹萨综合征的阿尔茨海默病患者。这些患者在一项上市后监测研究中接受了胆碱酯酶抑制剂治疗。这些患者的临床和用药史表明胆碱酯酶抑制剂与侧倾性肌张力障碍之间存在关联。胆碱酯酶抑制剂在痴呆治疗中的广泛使用可能导致匹萨综合征病例增多。