Varela Gonzalo, Jiménez Marcelo F, Novoa Nuria, Aranda José L
Section of Thoracic Surgery, Salamanca University Hospital, 37007 Salamanca, Paseo de San Vicente 58, Spain.
Eur J Cardiothorac Surg. 2005 Feb;27(2):329-33. doi: 10.1016/j.ejcts.2004.11.005.
Prolonged air leak (PAL) after pulmonary surgery is a frequent occurrence and is reported to cause increased length of stay (LOS) and hospital costs although the costs directly attributable to PAL have never been published. The present study aims to compare the prevalence of pulmonary complications (atelectasis, pneumonia and pleural empyema) in patients with or without PAL and to quantify economic costs directly incurred by PAL in a series of pulmonary lobectomies.
A series of 238 patients scheduled for pulmonary lobectomy (January 2001-December 2003) have been reviewed. PAL was defined as air leakage which prevented hospital discharge for 5 postoperative days or over. Hospital costs (excluding operating room) for pulmonary lobectomies have been obtained and calculated as mean daily costs. Age, body mass index, diagnosis, Charlson co-morbidity index, ppoFEV1 and major post-operative cardio-pulmonary morbidity have been used to construct a Cox-regression model for hospital stay, considering deaths as censored cases. Individual risk function has been used as a new variable and expected LOS calculated for each case. This data has been used to estimate total excess hospital stay and costs incurred by cases with PAL.
Prevalence of PAL was 23 cases (9, 7%). Mean daily hospital cost for lobectomy was 632.49. For the whole series, mean hospital stay was 5 days (10 days for patients with PAL). PAL cases had more postoperative pulmonary morbidity (risk-ratio: 2.78). Variables showing independent influence on stay were: diagnosis of non-malignant disease (P=0.001); FEV1ppo (P=0.032) and cardio-respiratory morbidity (P<0.001). Calculated total excess stay for PAL patients was 62 days. A total expense of 39,437.39 (38,724.96 hospital and 712.43 pharmacy charges) were estimated to result from postoperative air-leak.
PAL patients are prone to developing major postoperative morbidity. PAL calculated costs are over 13,000 per year. This data is useful for designing technical cost-effective strategies to avoid post-lobectomy PAL.
肺手术后的持续性漏气(PAL)很常见,据报道会导致住院时间(LOS)延长和医院成本增加,尽管PAL直接导致的成本从未公布过。本研究旨在比较有或无PAL患者的肺部并发症(肺不张、肺炎和胸膜脓胸)的发生率,并量化一系列肺叶切除术中PAL直接产生的经济成本。
回顾了2001年1月至2003年12月计划进行肺叶切除术的238例患者。PAL定义为术后漏气持续5天或更长时间导致无法出院。已获取并计算肺叶切除术的医院成本(不包括手术室),以日均成本计算。年龄、体重指数、诊断、Charlson合并症指数、ppoFEV1和主要术后心肺发病率被用于构建住院时间的Cox回归模型,将死亡视为删失病例。个体风险函数被用作一个新变量,并为每个病例计算预期住院时间。这些数据被用于估计PAL病例的总额外住院时间和成本。
PAL的发生率为23例(9.7%)。肺叶切除术的日均医院成本为632.49。对于整个系列,平均住院时间为5天(PAL患者为10天)。PAL病例术后肺部并发症更多(风险比:2.78)。对住院时间有独立影响的变量为:非恶性疾病诊断(P = 0.001);FEV1ppo(P = 0.032)和心肺发病率(P < 0.001)。PAL患者计算出的总额外住院时间为62天。术后漏气估计导致总费用39437.39(医院费用38724.96和药房费用712.43)。
PAL患者术后易发生严重并发症。PAL计算出的成本每年超过13000。这些数据有助于设计技术上具有成本效益的策略以避免肺叶切除术后的PAL。