平面极性的数学建模

Mathematical modeling of planar polarity.

作者信息

Strutt David

机构信息

Centre for Developmental and Biomedical Genetics, Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

出版信息

Dev Cell. 2005 Feb;8(2):134-6. doi: 10.1016/j.devcel.2005.01.007.

DOI:10.1016/j.devcel.2005.01.007

PMID:15691754

Abstract

Although it is well established that the Frizzled receptor is involved in the transmission of polarity information from cell to cell in the Drosophila cuticle, its precise role is still unclear. A recent paper by presents a mathematical model of a feedback loop-based mechanism for propagation of polarity between cells that can account for the known functions of Frizzled.

摘要

虽然已经充分证实卷曲受体在果蝇表皮中参与细胞间极性信息的传递，但其确切作用仍不清楚。最近一篇论文提出了一种基于反馈回路的细胞间极性传播机制的数学模型，该模型可以解释卷曲受体的已知功能。