短暂性低血糖诱发偏瘫时表观扩散系数的局部可逆性降低
Localized reversible reduction of apparent diffusion coefficient in transient hypoglycemia-induced hemiparesis.
作者信息
Böttcher J, Kunze A, Kurrat C, Schmidt P, Hagemann G, Witte O W, Kaiser W A
机构信息
Department of Diagnostic and Interventional Radiology, Friedrich-Schiller-University Jena, Erlanger Allee 101, 07747 Jena, Germany.
出版信息
Stroke. 2005 Mar;36(3):e20-2. doi: 10.1161/01.STR.0000155733.65215.c2. Epub 2005 Feb 3.
BACKGROUND AND PURPOSE
The pathophysiology of hypoglycemia shares a common mechanism with cerebral ischemia, but so far, little is known regarding MRI of humans with hypoglycemia.
METHODS
We report a patient with left hemiparesis and dysarthria associated with a blood glucose level of 1.7 mmol/L. The patient recovered completely after glucose infusion.
RESULTS
The initial diffusion-weighted imaging (DWI) showed increased signal intensities and a reduction of apparent diffusion coefficient (ADC) values localized in the corpus callosum (splenium) and asymmetrically in the corona radiata. After 48 hours, follow-up revealed complete recovery of DWI and ADC signal abnormalities.
CONCLUSIONS
To our knowledge, this is the first presentation of a case with transient hypoglycemia-induced focal neurological deficits revealing completely reversible MRI changes in terms of disturbed DWI and ADC with a peculiar as yet undescribed topography.
背景与目的
低血糖的病理生理学与脑缺血具有共同机制，但迄今为止，关于低血糖患者的磁共振成像（MRI）情况知之甚少。
方法
我们报告1例血糖水平为1.7 mmol/L且伴有左侧偏瘫和构音障碍的患者。输注葡萄糖后患者完全康复。
结果
初始扩散加权成像（DWI）显示胼胝体（压部）及不对称性放射冠出现信号强度增加和表观扩散系数（ADC）值降低。48小时后随访发现DWI及ADC信号异常完全恢复。
结论
据我们所知，这是首例有短暂低血糖诱发局灶性神经功能缺损的病例报道，其显示出DWI和ADC紊乱具有完全可逆的MRI变化，且具有一种特殊的、尚未描述的影像学表现。
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