低血糖危象的病理生理学与病因学
Pathophysiology and aetiology of hypoglycaemic crises.
作者信息
Morgan R K, Cortes Y, Murphy L
机构信息
Metropolitan Veterinary Associates, Norristown, Pennsylvania, USA.
Emergency Department, Oradell Animal Hospital, Paramus, New Jersey, USA.
出版信息
J Small Anim Pract. 2018 Nov;59(11):659-669. doi: 10.1111/jsap.12911. Epub 2018 Aug 13.
Abstract
Hypoglycaemia is a common, life-threatening complication that occurs as a component of a wide variety of disease processes. Despite its frequent occurrence, information concerning the aetiology, characteristics and outcomes of hypoglycaemic crises in veterinary medicine is limited. This review summarises the current understanding of the pathophysiology of hypoglycaemia, the body's counter-regulatory response, underlying aetiologies, diagnosis and treatment. Disease mechanisms are discussed and published evidence in veterinary literature regarding prognostic indicators, prevalence, diagnosis and treatment is examined for hypoglycaemia-related disease processes including insulinoma, glucose-lowering toxins and medications.
摘要
低血糖是一种常见的、危及生命的并发症，是多种疾病过程的组成部分。尽管其频繁发生，但兽医学中关于低血糖危象的病因、特征和结局的信息有限。本综述总结了目前对低血糖病理生理学、机体反调节反应、潜在病因、诊断和治疗的理解。讨论了疾病机制，并研究了兽医文献中关于胰岛素瘤、降糖毒素和药物等低血糖相关疾病过程的预后指标、患病率、诊断和治疗的已发表证据。
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