艾滋病合并隐球菌性脑膜炎患者的颅内压升高及视觉并发症

Raised intracranial pressure and visual complications in AIDS patients with cryptococcal meningitis.

作者信息

Johnston S R, Corbett E L, Foster O, Ash S, Cohen J

机构信息

Infectious Diseases Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.

出版信息

J Infect. 1992 Mar;24(2):185-9. doi: 10.1016/0163-4453(92)92954-h.

DOI:10.1016/0163-4453(92)92954-h

PMID:1569310

Abstract

The clinical course of cryptococcal meningitis in AIDS shows some important differences from the features of the illness in non-AIDS patients. Complications such as raised intracranial pressure and visual impairment that are recognised in non-AIDS patients may be less frequent in those with AIDS. Persistent intracranial hypertension should be managed actively to prevent visual impairment. In AIDS patients, in whom ventriculo-peritoneal shunts carry additional risks, acetazolamide can be used successfully to lower the CSF pressure and prevent visual loss.

摘要

艾滋病患者隐球菌性脑膜炎的临床病程与非艾滋病患者的疾病特征存在一些重要差异。非艾滋病患者中公认的颅内压升高和视力损害等并发症在艾滋病患者中可能较少见。应积极处理持续性颅内高压以预防视力损害。在脑室-腹腔分流术存在额外风险的艾滋病患者中，乙酰唑胺可成功用于降低脑脊液压力并预防视力丧失。