用于测量冠心病患者左心室容积和射血分数的旋转扫描徒手三维超声心动图。

Freehand three-dimensional echocardiography with rotational scanning for measurements of left ventricular volume and ejection fraction in patients with coronary artery disease.

作者信息

Fukuda Shota, Hozumi Takeshi, Watanabe Hiroyuki, Muro Takashi, Yamagishi Hiroyuki, Yoshiyama Minoru, Takeuchi Kazuhide, Yoshikawa Junichi

机构信息

Department of Internal Medicine and Cardiology, Osaka City University School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.

出版信息

Echocardiography. 2005 Feb;22(2):111-9. doi: 10.1111/j.0742-2822.2005.03168.x.

DOI:10.1111/j.0742-2822.2005.03168.x

PMID:15693776

Abstract

BACKGROUND

Measurement of left ventricular (LV) volumes and ejection fraction (EF) is important in managing patients with coronary artery disease (CAD). Introduction of free-hand three-dimensional echocardiography (3DE) system which is equipped with small magnetic tracking system and average rotational geometry for LV volumes may provide easy and accurate quantification of LV systolic function in CAD patients.

PURPOSE

To evaluate the feasibility and accuracy of LV volumes and EF measurement by free-hand 3DE with rotational geometry in patients with CAD.

METHODS AND RESULTS

The study subjects consisted of consecutive 25 patients with CAD who were scheduled for quantitative gated single-photon emission computed tomography (QGS). LV end-diastolic volume (EDV), end-systolic volume (ESV), and EF were determined by conventional two-dimensional echocardiography (2DE), 3DE, and QGS. Three-dimensional echocardiography data acquisition and analysis were possible in 22 of 25 subjects (feasibility 88%). In this 3DE system, image acquisition time was 2 minutes, and 5 minutes were needed for off-line analysis of LV volumes and EF. Correlations and the limits of agreement between 3DE and QGS (r = 0.97, 0.0 +/- 9.1 ml for EDV, r = 0.99, 0.0 +/- 5.0 ml for ESV, and r = 0.97, 0.5 +/- 3.3% for EF, respectively) were superior to those between 2DE and QGS (r = 0.85, 12.6 +/- 26.8 ml for EDV, r = 0.85, 9.7 +/- 26.1 ml for ESV, and r = 0.90, -1.3 +/- 6.9% for EF, respectively). Inter- and intra-observer variabilities of 3DE were smaller than that of 2DE (5% vs 10%, 5% vs 10% for EDV, 6% vs 13%, 5% vs 9% for ESV, and 4% vs 11%, 4% vs 6% for EF, respectively).

CONCLUSION

Three-dimensional echocardiography using magnetic tracking system and average rotational geometry offered a feasible and accurate method for quantification of LV volumes and EF in patients with CAD.

摘要

背景

测量左心室（LV）容积和射血分数（EF）对于管理冠状动脉疾病（CAD）患者很重要。配备小型磁跟踪系统和用于LV容积的平均旋转几何结构的徒手三维超声心动图（3DE）系统，可能为CAD患者左心室收缩功能提供简便且准确的定量评估。

目的

评估在CAD患者中使用具有旋转几何结构的徒手3DE测量LV容积和EF的可行性和准确性。

方法与结果

研究对象包括连续25例计划接受定量门控单光子发射计算机断层扫描（QGS）的CAD患者。通过传统二维超声心动图（2DE）、3DE和QGS测定左心室舒张末期容积（EDV）、收缩末期容积（ESV）和EF。25例受试者中有22例可以进行三维超声心动图数据采集和分析（可行性88%）。在这个3DE系统中，图像采集时间为2分钟，离线分析LV容积和EF需要5分钟。3DE与QGS之间的相关性和一致性界限（EDV的r = 0.97，0.0±9.1 ml；ESV的r = 0.99，0.0±5.0 ml；EF的r = 0.97，0.5±3.3%）优于2DE与QGS之间的相关性和一致性界限（EDV的r = 0.85，12.6±26.8 ml；ESV的r = 0.85，9.7±26.1 ml；EF的r = 0.90，-1.3±6.9%）。3DE的观察者间和观察者内变异性小于2DE（EDV分别为5%对10%，5%对10%；ESV分别为6%对13%，5%对9%；EF分别为4%对11%，4%对6%）。