[Treatment of adult prostate sarcoma: a report of six cases with literature review].

BACKGROUND & OBJECTIVE: Primary adult prostate sarcoma is rare. Most patients come to hospital with huge pelvic tumors. Treatment for this disease remains controversial. We reported our experience of treating 6 cases of adult prostate sarcoma, and explore reasonable therapy strategy with literature review.

METHODS

Six adult patients with prostate sarcoma were treated in our hospital, 5 underwent cystoprostatectomy combined with urinary diversion, 1 underwent total pelvic exenteration combined with urinary diversion and colostomy; 3 had preoperative intervention to embolize bilateral internal iliac artery, 4 received postoperative radiotherapy. The recent 11 reports published in China with a total of 62 cases were reviewed, 32 of them had radical surgery. The pertinent literatures from other countries were also reviewed.

RESULTS

Of our 6 patients, 1 survived with no evidence of disease for 33 months; 1 survived with recurrent tumor for 18 months; 4 died of recurrent sarcoma 5-40 months after surgery. In the whole group of 62 patients, 1-, and 2-year survival rates were 59%, and 34%.

CONCLUSION

Up to now, radical surgery is the most effective treatment for adult prostate sarcoma.