Wang Qun, Xia Xin, Yuan Hui-Juan
Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Di Yi Jun Yi Da Xue Xue Bao. 2005 Feb;25(2):223-5.
To explore the changes of cerebral hemodynomics in patients with virus encephalitis (VE).
Within the initial 24 h and 21 days after admission, respectively, the patients with acute VE (n=38) suspected to result from viral infections were examined with serial transcranial Doppler ultrasound (TCD) for measurements of the systolic flow velocity (Vs), mean blood velocity (Vm) and the pulsatility index (PI) in the middle, anterior and posterior cerebral arteries (MCA, ACA, PCA) and the basilar artery (BA).
TCD showed normal findings in 11 and abnormal findings in 27 patients, with a positivity rate of 71%. The Vms were significantly elevated in MCA, ACA, PCA, vertebral artery and BA during the acute phase of VE compared with that of the 30 normal control subjects (P<0.001-0.05). The PIs were significantly increased in MCA, PCA and BA (P<0.001).
TCD findings indicate the presence of cerebral vasospasm in VE during the acute phase.
探讨病毒性脑炎（VE）患者脑血流动力学变化。
分别于入院后最初24小时内及21天时，对38例疑似病毒感染所致急性VE患者采用经颅多普勒超声（TCD）连续检测大脑中动脉（MCA）、大脑前动脉（ACA）、大脑后动脉（PCA）及基底动脉（BA）的收缩期血流速度（Vs）、平均血流速度（Vm）及搏动指数（PI）。
TCD检查结果显示，11例正常，27例异常，阳性率为71%。与30例正常对照者相比，VE急性期时MCA、ACA、PCA、椎动脉及BA的Vm显著升高（P<0.001 - 0.05）。MCA、PCA及BA的PI显著增加（P<0.001）。
TCD检查结果提示VE急性期存在脑血管痉挛。
