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[孕前体重及孕期体重增加与妊娠期高血压和出生体重的关系]

[Relations of pre-pregnant weight and weight gain during pregnancy with pregnancy-induced hypertension and birth weight].

作者信息

Yin Yu-Zhu, Chen Xiao-Wei, Li Xiao-Mao, Hou Hong-Ying, Zhou Shui-Sheng

机构信息

Department of Obstetrics and Gynecology, Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.

出版信息

Di Yi Jun Yi Da Xue Xue Bao. 2005 Feb;25(2):226-8.

Abstract

OBJECTIVE

To determine the influence of pre-pregnant body mass index (BMI) and weight gain during pregnancy on the occurrence of pregnancy-induced hypertension (PIH) and birth weight.

METHODS

Pre-pregnant BMI and pregnancy weight gain of 769 mothers giving full-term birth to a single baby for the first time were measured and the pregnancy outcomes were followed up.

RESULTS

(1) The incidence of PIH and fetal macrosomia was significantly higher in the overweight group than in the normal weight and underweight groups (P<0.01 and P<0.05, respectively), but differed little between the latter two groups (P>0.05). Underweight mothers were more likely to give birth to babies with low birth weight than the normal and overweight mothers (P<0.01), but the likelihood was similar between the latter two groups (P>0.05). (2) Irrespective of the pre-pregnant BMI, PIH and fetal macrosomia occurred at higher rates with the mothers with pregnancy weight gain no less than 18 kg (P<0.01), whereas low birth weight was significantly more likely with mothers with pregnancy weight gain less than 9 kg (P<0.01). (3) A weight gain during pregnancy over 18 kg gave rise to higher risk of PIH in normal and underweight mothers, but in overweight group, PIH occurred at a significantly higher rates when a weight gain more than 9 kg was recorded (P<0.05). The incidence of fetal macrosomia was significantly higher when the maternal weight gain exceeded 18 kg in the normal weight group (P<0.01), and low birth weight occurred more frequently in relation to a maternal weight gain less than 9 kg in the normal and underweight groups (P<0.01).

CONCLUSION

Pre-pregnant BMI and weight gain during pregnancy can be important factors influencing the occurrence of PIH and the neonates' birth weight.

摘要

目的

确定孕前体重指数(BMI)及孕期体重增加对妊娠高血压综合征(PIH)发生情况及出生体重的影响。

方法

测量769例首次足月单胎分娩母亲的孕前BMI及孕期体重增加情况,并对妊娠结局进行随访。

结果

(1)超重组PIH及巨大儿发生率显著高于正常体重组和低体重组(分别为P<0.01和P<0.05),但后两组间差异不大(P>0.05)。低体重母亲比正常体重和超重母亲更易分娩低出生体重儿(P<0.01),但后两组间可能性相似(P>0.05)。(2)无论孕前BMI如何,孕期体重增加不少于18 kg的母亲发生PIH及巨大儿的比例更高(P<0.01),而孕期体重增加少于9 kg的母亲分娩低出生体重儿的可能性显著更高(P<0.01)。(3)孕期体重增加超过18 kg使正常体重和低体重母亲发生PIH的风险升高,但在超重组,体重增加超过9 kg时PIH发生率显著更高(P<0.05)。正常体重组中母亲体重增加超过18 kg时巨大儿发生率显著更高(P<0.01),正常体重和低体重组中母亲体重增加少于9 kg时低出生体重儿更频繁出现(P<0.01)。

结论

孕前BMI及孕期体重增加可能是影响PIH发生及新生儿出生体重的重要因素。

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