Plus R
Med Hypotheses. 1992 Jan;37(1):49-57. doi: 10.1016/0306-9877(92)90014-4.
Clinical applications of porphyrins lead research biologists to characterize these compounds according to their fluorescence. These measurements revealed unexpected fluorescence spectra in addition to those of the injected porphyrins. The general characteristics of the spectra of porphyrins are reviewed. The technique permitting studies on animals in a waking state and the advantages of this method are shown. The studies in this field are reviewed and spectra reproduced. Among the observed fluorescences, those which cannot be attributed to injected porphyrins are divided into two groups. The first group, above 580 nm, seems to result from molecular associations (polymers or micelles of injected porphyrins). The second group, from 560-575 nm, seems to belong to a natural compound. Some spectroscopic observations and some medical reports lead us to identify it as an unusual natural porphyrin and perhaps as metalloporphyrin. Some authors have mentioned a Zn porphyrin. Finally, the importance of continuing the study of this natural porphyrin is discussed.
卟啉的临床应用促使研究生物学家根据其荧光特性对这些化合物进行表征。这些测量结果除了显示注入的卟啉的荧光光谱外，还揭示了意想不到的荧光光谱。本文综述了卟啉光谱的一般特征。展示了在清醒状态下对动物进行研究的技术及其优势。对该领域的研究进行了综述并重现了光谱。在观察到的荧光中，那些不能归因于注入的卟啉的荧光被分为两组。第一组，波长在580nm以上，似乎是由分子缔合（注入的卟啉的聚合物或胶束）产生的。第二组，波长在560 - 575nm之间，似乎属于一种天然化合物。一些光谱观察和医学报告使我们将其鉴定为一种不寻常的天然卟啉，可能是金属卟啉。一些作者提到了一种锌卟啉。最后，讨论了继续研究这种天然卟啉的重要性。
