Rosser Tena L, Vezina Gilbert, Packer Roger J
Department of Neurology, Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, The George Washington University, 111 Michigan Avenue NW, Washington, DC 20010, USA.
Neurology. 2005 Feb 8;64(3):553-5. doi: 10.1212/01.WNL.0000150544.00016.69.
Neurofibromatosis type 1 (NF1) is associated with vasculopathy, which may result in a variety of cerebrovascular complications. The purpose of this study was to evaluate the spectrum of cerebrovascular disease in a pediatric population with NF1. Of 316 patients with NF1 who underwent brain MRI, 8 (2.5%) children were reported to have an abnormality of the cerebrovascular system, including narrowed or ectatic vessels, vascular stenoses, aneurysm, and moyamoya.
1型神经纤维瘤病（NF1）与血管病变有关，这可能导致多种脑血管并发症。本研究的目的是评估患有NF1的儿科人群中的脑血管疾病谱。在316例接受脑部MRI检查的NF1患者中，有8例（2.5%）儿童被报告存在脑血管系统异常，包括血管狭窄或扩张、血管狭窄、动脉瘤和烟雾病。
