Choukroun Gabriel, Martinez Frank
Nephrology Department, Amiens University Hospital, Amiens, France.
Transplantation. 2005 Feb 15;79(3 Suppl):S49-50. doi: 10.1097/01.tp.0000153304.39865.6e.
Anemia is a common complication in patients with chronic kidney diseases (CKD), including transplanted patients. Recent studies have found a prevalence of anemia of about 30%, whereas less than 10% of these patients received recombinant human erythropoietin. Factors explaining this high incidence of anemia in renal transplant recipients include delayed and impaired graft function and use of drugs inhibiting the action of angiotensin II and preventing rejection. Like in CKD patients, chronic anemia may impact on the cardiovascular system and finally on the high mortality of these patients. Recent data suggest also that anemia may be a factor of progression of renal dysfunction in kidney transplant recipients. A French randomized multicenter study was designed to answer this question.
贫血是慢性肾脏病（CKD）患者（包括肾移植患者）的常见并发症。最近的研究发现贫血患病率约为30%，而这些患者中接受重组人促红细胞生成素治疗的不到10%。肾移植受者贫血发生率高的原因包括移植肾功能延迟和受损，以及使用抑制血管紧张素II作用和预防排斥反应的药物。与CKD患者一样，慢性贫血可能影响心血管系统，最终导致这些患者的高死亡率。最近的数据还表明，贫血可能是肾移植受者肾功能不全进展的一个因素。一项法国随机多中心研究旨在回答这个问题。
