Solbiati Luigi, Tonolini Massimo, Cova Luca
Department of Radiology, General Hospital, 21052 Busto Arsizio (VA), Italy.
Eur Radiol. 2004 Oct;14 Suppl 8:P34-42. doi: 10.1007/s10406-004-0089-y.
The addition of contrast-enhanced ultrasound to monitor the extent of interstitial ablation has simplified this procedure. Newer agents such as SonoVue used with microbubble-specific software (CPS) allow continuous real-time scanning at low MIs so that, if residual perfused tumour is found, complete evaluation of the extent of tissue ablation can be carried out immediately after the procedure in the same treatment session. In the initial 18-month period after the introduction of these agents, partial necrosis occurred in 5.1% of treated lesions compared to the previous rate of 16.1%, and this improved to 3.8% in the following 2 years. The method is cost-effective because it reduces the need for repeated treatment sessions under general anaesthesia. The same method is helpful in treatment planning and follow-up.
添加超声造影剂以监测间质消融范围简化了这一操作过程。新型造影剂如声诺维与特定微泡软件(CPS)联合使用,可在低机械指数下进行连续实时扫描,这样,如果发现有残余灌注肿瘤,在同一治疗疗程中,可在操作完成后立即对组织消融范围进行全面评估。在引入这些造影剂后的最初18个月里,治疗的病灶中有5.1%发生部分坏死,而之前这一比例为16.1%,在接下来的两年中这一比例降至3.8%。该方法具有成本效益,因为它减少了在全身麻醉下重复治疗疗程的需求。同样的方法对治疗规划和随访也有帮助。