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多层螺旋CT在基底动脉急性闭塞中的诊断性血管造影

[Diagnostic angiography using multi-slice spiral CT in acute obstruction of the basilar artery].

作者信息

Schmitt R, Christopoulos G, Salveter E, Ziegler V, Brunner H, Wedell E, Griewing B

机构信息

Institut für Diagnostische und Interventionelle Radiologie, Herz- und Gefassklinik GmbH Bad Neustadt an der Saale.

出版信息

Rontgenpraxis. 2004;55(5):184-91.

Abstract

OBJECTIVE

To evaluate the diagnostic efficiency of CT angiography in case of clinical signs of acute brainstem infarction for the therapeutic management of catheter-based local thrombolysis.

MATERIAL AND METHODS

3 patients (2 males, 1 female) suffering from an acute onset of brainstem symptoms and being suspicious of an occluded basilar artery were included into this report. 1 patient underwent selective vertebral arteriography. 2 patients were initially examined with CT angiography using a 4-row scanner and 100 ml intravenous contrast agent.

RESULTS

In one patient, an occlusion of the basilar artery was excluded with catheter-based angiography. Subsequently, the patient was treated with systemic thrombolysis using r-tPA because of a thalamus infarction seen in MRI. 2 patients who have been initially examined with CT angiography presented with complete occlusions of the basilar arteries. These patients underwent r-tPA thrombolysis by means of superselective micro-catheter approaches of the vertebrobasilar vessels. CT angiography was very useful for determinating the occlusion length of the basilar artery pre-therapeutically, and in 1 case for ruling out an occluded vertrebral artery for catheterization. All patients recovered well under thrombolytic therapy applied systemically or selectively.

CONCLUSION

Cerebral multi-slice CT angiography is a fast and save technique for detecting or ruling out an acute basilar artery occlusion. Thus, in cases of equivocal clinical signs CT angiography is recommended before the decision of thrombolytic therapy is made.

摘要

目的

评估CT血管造影在急性脑干梗死临床症状情况下对基于导管的局部溶栓治疗管理的诊断效率。

材料与方法

本报告纳入3例(2男1女)急性起病的脑干症状且怀疑基底动脉闭塞的患者。1例患者接受了选择性椎动脉造影。2例患者最初使用4排扫描仪和100 ml静脉造影剂进行了CT血管造影检查。

结果

1例患者经导管血管造影排除了基底动脉闭塞。随后,该患者因MRI显示丘脑梗死接受了使用重组组织型纤溶酶原激活剂(r-tPA)的全身溶栓治疗。最初接受CT血管造影检查的2例患者表现为基底动脉完全闭塞。这些患者通过椎基底血管的超选择性微导管方法接受了r-tPA溶栓治疗。CT血管造影对于治疗前确定基底动脉的闭塞长度非常有用,在1例中用于排除用于导管插入术的椎动脉闭塞。所有患者在全身或选择性溶栓治疗下恢复良好。

结论

脑多层CT血管造影是检测或排除急性基底动脉闭塞的快速且安全的技术。因此,在临床症状不明确的情况下,建议在决定溶栓治疗之前进行CT血管造影。

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