Finn D A, Crabbe J C
Department of Behavioral Neuroscience, Oregon Health Sciences University, Portland, Oregon, USA.
Alcohol Health Res World. 1997;21(2):149-56.
Alcohol withdrawal syndrome is characterized by hyperactivity of the nervous system. This hyperactivity represents the brain's attempt to function normally despite the inhibitory effect of chronic alcohol consumption. The syndrome manifests when alcohol consumption ceases. Experimental, clinical, and genetic research have linked the development of withdrawal to alterations in the sensitivity of neuronal communication systems. Early treatment of the syndrome is advised, because the symptom severity may increase with each subsequent episode.
酒精戒断综合征的特征是神经系统活动亢进。这种活动亢进代表了尽管长期饮酒具有抑制作用,但大脑仍试图正常运作。该综合征在停止饮酒时出现。实验、临床和遗传学研究已将戒断反应的发生与神经元通讯系统敏感性的改变联系起来。建议对该综合征进行早期治疗,因为症状严重程度可能会随着后续发作而增加。