单原核卵母细胞形成的卵裂期胚胎移植后单卵双胎分娩。
Monozygotic twin birth after the transfer of a cleavage stage embryo resulting from a single pronucleated oocyte.
作者信息
Dasig Daniel, Lyon Jennifer, Behr Barry, Milki Amin A
机构信息
Stanford University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Palo Alto, California 94304, USA.
出版信息
J Assist Reprod Genet. 2004 Dec;21(12):427-9. doi: 10.1007/s10815-004-8758-2.
Abstract
PURPOSE
To present a case involving the transfer of a single pronucleated oocyte resulting in a monozygotic twin pregnancy.
METHOD
A descriptive case report of a single patient.
RESULTS
The patient conceived and was found to have a monochorionic diamnionic pregnancy which resulted in the birth of normal identical twin boys at 32 weeks of gestation.
CONCLUSIONS
The case report addresses an issue that has not received proper attention in the literature. It illustrates that observing a single PN in an oocyte at fertilization check should not be an absolute deterrent to transferring the resulting embryo even in an older patient with a high FSH level. This report also suggests that single observations, especially at the assessment of fertilization, in the IVF laboratory are limited when evaluating embryo potential and normalcy.
摘要
目的
介绍一例涉及单原核卵母细胞移植导致单卵双胎妊娠的病例。
方法
对一名患者的描述性病例报告。
结果
该患者怀孕，被发现为单绒毛膜双羊膜囊妊娠，妊娠32周时产下正常的同卵双胞胎男孩。
结论
该病例报告涉及一个在文献中未得到适当关注的问题。它表明，即使是在促卵泡激素水平高的老年患者中，在受精检查时观察到卵母细胞中有单个原核，也不应绝对阻碍移植由此产生的胚胎。本报告还表明，在体外受精实验室中，特别是在评估受精情况时的单次观察，在评估胚胎潜力和正常性方面是有限的。
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