Dubey Deepak, Kumar Anant, Mandhani Anil, Srivastava Aneesh, Kapoor Rakesh, Bhandari Mahendra
Department of Urology and Renal Transplant, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
BJU Int. 2005 Mar;95(4):625-9. doi: 10.1111/j.1464-410X.2005.05352.x.
To present our experience with buccal mucosa urethroplasty for substitution of all segments of the anterior urethra, as the buccal mucosal graft (BMG) has emerged as the tissue of choice for single-stage reconstruction of bulbar urethral strictures, but its use for reconstructing meatal, pendulous and pan-urethral strictures has not been widely reported.
Between January 1998 and October 2003, 92 patients had a BMG substitution urethroplasty at our institution; 75 had a single-stage dorsal onlay BMG urethroplasty (bulbar 41, pendulous 16 and pan-urethral 18; six combined penile skin flap and BMG) and 17 (pendulous five, pan-urethral 10, bulbar two) a two-stage urethroplasty. Recurrence rates, complications and cosmetic outcomes were analysed retrospectively.
Over a median (range) follow-up of 34 (8-72) months, 66 (88%) patients with a one-stage reconstruction (14/16 pendulous; 37/41, 90%, bulbar; 15/16 pan-urethral) remained stricture-free. The mean (range) time to recurrence was 9.4 (3-17) months. Of the nine recurrent strictures, six were managed by one-stage optical urethrotomy and three required a repeat urethroplasty. In patients who had a staged procedure, after a mean follow-up of 24.2 (9-56) months, one had complete graft loss, requiring re-grafting, five required stomal revision after stage 1, and only two (12%) developed a recurrent stricture after the two-stage urethroplasty.
A one-stage dorsal onlay BMG urethroplasty provides excellent results for strictures involving any segment of the anterior urethra. The BMG appears to be the most versatile urethral substitute, as it can be successfully used for both one- and two-stage reconstruction of the entire anterior urethra.
介绍我们应用颊黏膜尿道成形术替代前尿道各段的经验,因为颊黏膜移植物(BMG)已成为一期重建球部尿道狭窄的首选组织,但其用于重建尿道口、悬垂部及全尿道狭窄的报道并不广泛。
1998年1月至2003年10月期间,92例患者在我院接受了BMG替代尿道成形术;75例行一期背侧镶嵌式BMG尿道成形术(球部41例、悬垂部16例、全尿道18例;6例联合阴茎皮瓣和BMG),17例(悬垂部5例、全尿道10例、球部2例)行二期尿道成形术。对复发率、并发症及美容效果进行回顾性分析。
中位(范围)随访34(8 - 72)个月,66例(88%)一期重建患者(悬垂部14/16;球部37/41,90%;全尿道15/16)无狭窄复发。复发的平均(范围)时间为9.4(3 - 17)个月。9例复发性狭窄中,6例通过一期光学尿道切开术处理,3例需要再次尿道成形术。在接受分期手术的患者中,平均随访24.2(9 - 56)个月后,1例出现完全移植物丢失,需要重新移植,5例在第一阶段后需要进行造口修复,只有2例(12%)在二期尿道成形术后出现复发性狭窄。
一期背侧镶嵌式BMG尿道成形术对累及前尿道任何节段的狭窄均能取得优异效果。BMG似乎是最通用的尿道替代物,因为它可成功用于全前尿道的一期和二期重建。