血管与神经：协同运作。

Vessels and nerves: marching to the same tune.

作者信息

Weinstein Brant M

机构信息

National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

出版信息

Cell. 2005 Feb 11;120(3):299-302. doi: 10.1016/j.cell.2005.01.010.

DOI:10.1016/j.cell.2005.01.010

PMID:15707889

Abstract

The patterning of the nervous system is achieved through coordinated action of a variety of repulsive or attractive neuronal guidance factors that direct the growth of growing axons to specific pathways. Recent studies suggest that the same or similar sets of factors also guide migration of endothelial cells, helping to direct the stereotypical embryonic patterning of the developing vertebrate vascular system.

摘要

神经系统的模式形成是通过多种排斥性或吸引性神经元导向因子的协同作用实现的，这些因子引导生长中的轴突生长至特定路径。最近的研究表明，相同或相似的因子组合也指导内皮细胞的迁移，有助于引导发育中的脊椎动物血管系统形成典型的胚胎模式。