Janik R, Dick W
Klinik für Anaesthesiologie, Johannes Gutenberg-Universität Mainz.
Anaesthesist. 1992 Mar;41(3):137-41.
A lack of uniform methodology used by different authors in the assessment of different puncture techniques in spinal anesthesia formed the basis of the current study, which compared under randomized conditions the incidence of post spinal headache after a median or paramedian (lateral) approach. MATERIALS AND METHODS. Two hundred and fifty ASA physical status II and III patients, aged 50-85 years, scheduled for transurethral prostate surgery under spinal anesthesia were investigated. The patients were comparable with regard to weight and height (Table 1). No premedication was given and, 30 min prior to surgery, all patients received normal saline 400-500 ml i.v. The patients were randomly divided into two groups of 125 patients each to receive 4 ml 0.5% bupivacaine in 5% glucose (specific gravity 1.017 at 20 degrees C) using the median or paramedian (lateral) approach according to the following scheme (Table 2): I: 4 ml 0.5% bupivacaine/median approach; II: 4 ml 0.5% bupivacaine/paramedian approach. The study was carried out in a double-blind fashion. Neither the patient nor the investigator evaluating the post spinal headache was aware of which technique had been used. Lumbar puncture was performed by a midline approach at the L3-4 interspace using a 25-gauge (Whitacre) spinal needle with the patient in the sitting position group I. The bevel of the spinal needle was directly laterally, so that the dural fibers that run longitudinally were spread rather than transected. When using the paramedian approach (group II), patients were placed in the flexed lateral decubitus position and the spinal needle inserted 1 cm medial and 1 cm lateral and caudad to the lowest part of the posterior superior iliac spine and then directed medially and cephalad at an angle of 55 degrees into the subarachnoid space. Postoperatively, patients were allowed to move as soon as possible; no prophylactic bed rest was ordered. Starting from the 1st postoperative day, patients were evaluated by an independent observer and asked whether they were suffering from any problems concerning anesthesia. Typical post-puncture headache was defined as invariably bifrontal and occipital, frequently involving the neck and upper shoulders, and being aggravated by the upright position. Statistical analysis of the data was performed using the Mann-Whitney rank-sum test for unpaired samples. A P value of less than 0.05 was considered statistically significant. RESULTS. Twenty-six of 250 patients (10.4%) developed post spinal headaches. Comparing both groups, 11/125 (8.8%) patients in the median group (group I) versus 15/125 (12%) in the paramedian group (group II) had typical post-puncture headaches. Within the group of patients aged 50-60 years, the paramedian approach (group II) showed a significantly higher headache rate compared with group I (P less than 0.05). Neurologic sequelae were not observed; 6 patients received epidural injections of autologous blood while the rest of the patients suffering from post spinal headache were treated conservatively with bed rest, analgesics, and fluids. CONCLUSIONS. The results indicate that the incidence of post spinal headache is higher in younger patients when using the paramedian (lateral) approach. However, our findings suggest that the choice of lumbar puncture technique--median or paramedian--is of little importance in regard to post-puncture headache in elderly patients. The paramedian approach is especially useful when degenerative changes are encountered in the interspinous structures in elderly patients, when an ideal position is difficult to achieve.
不同作者在评估脊髓麻醉不同穿刺技术时缺乏统一的方法,这构成了本研究的基础。本研究在随机条件下比较了正中或旁正中(侧方)入路后脊髓头痛的发生率。材料与方法。对250例年龄在50 - 85岁、ASA身体状况为II级和III级、计划在脊髓麻醉下进行经尿道前列腺手术的患者进行了研究。患者在体重和身高方面具有可比性(表1)。未给予术前用药,手术前30分钟,所有患者静脉输注400 - 500 ml生理盐水。患者被随机分为两组,每组125例,根据以下方案(表2)采用正中或旁正中(侧方)入路接受4 ml含5%葡萄糖的0.5%布比卡因(20℃时比重为1.017):I组:4 ml 0.5%布比卡因/正中入路;II组:4 ml 0.5%布比卡因/旁正中入路。研究采用双盲方式进行。患者和评估脊髓后头痛的研究者均不知道所采用的是哪种技术。I组患者取坐位,在L3 - 4椎间隙采用中线入路,使用25号(Whitacre)脊髓穿刺针进行腰椎穿刺。脊髓穿刺针的斜面直接朝向外侧,以使纵向走行的硬脊膜纤维散开而非横断。当采用旁正中入路(II组)时,患者取侧卧位屈膝,脊髓穿刺针在髂后上棘最低点内侧1 cm、外侧1 cm及尾侧进针,然后以55度角向内上方刺入蛛网膜下腔。术后,患者尽快允许活动;未安排预防性卧床休息。从术后第1天开始,由独立观察者对患者进行评估,并询问他们是否有与麻醉相关的任何问题。典型的穿刺后头痛定义为始终为双侧额部和枕部疼痛,常累及颈部和上肩部,且站立位时加重。采用Mann - Whitney秩和检验对未配对样本的数据进行统计分析。P值小于0.05被认为具有统计学意义。结果。250例患者中有26例(10.4%)发生了脊髓后头痛。比较两组,正中入路组(I组)11/125例(8.8%)患者与旁正中入路组(II组)15/125例(12%)患者出现典型的穿刺后头痛。在50 - 60岁的患者组中,旁正中入路组(II组)的头痛发生率明显高于I组(P小于0.05)。未观察到神经后遗症;6例患者接受了自体血硬膜外注射,其余患有脊髓后头痛的患者采用卧床休息、止痛药物和补液等保守治疗。结论。结果表明,采用旁正中(侧方)入路时年轻患者脊髓后头痛的发生率较高。然而,我们的研究结果表明,腰椎穿刺技术(正中或旁正中)的选择对于老年患者穿刺后头痛而言重要性不大。当老年患者棘突间结构出现退行性改变且难以获得理想体位时,旁正中入路尤其有用。