Gladman D D, Strand V, Mease P J, Antoni C, Nash P, Kavanaugh A
University of Toronto, Western Research Institute, Psoriatic Arthritis Program, Toronto Western Hospital, Ontario M5T 2S8, Canada.
Ann Rheum Dis. 2005 Mar;64 Suppl 2(Suppl 2):ii115-6. doi: 10.1136/ard.2004.032615.
Outcome Measures in Rheumatology (OMERACT) conferences have developed a process by which outcome measures to be included in clinical trials are identified by consensus. During OMERACT 7, held in Asilomar, CA, USA, in May 2004, a workshop on outcome measures in psoriatic arthritis was held. Information derived through a previous Delphi exercise and nominal group process was shared with the participants, as were the results from a study using completed clinical trials with biological therapies. On the basis of the evidence presented and discussions in breakout groups at the OMERACT conference, a set of domains to be included in clinical trials in psoriatic arthritis was developed and a research agenda for further studies in psoriatic arthritis proposed.
风湿病疗效评估核心组(OMERACT)会议制定了一个流程,通过该流程以共识方式确定纳入临床试验的疗效评估指标。2004年5月在美国加利福尼亚州阿西洛马举行的OMERACT 7会议期间,举办了一次关于银屑病关节炎疗效评估指标的研讨会。通过之前的德尔菲法和名义组技术得出的信息与参与者进行了分享,同时还分享了一项使用生物疗法完成的临床试验研究结果。基于OMERACT会议上提供的证据以及分组讨论,制定了一套纳入银屑病关节炎临床试验的领域,并提出了银屑病关节炎进一步研究的议程。