Le Bourg Eric
Chargé de recherche au CNRS, Centre de recherche sur la cognition animale, UMR CNRS 5169, Université Paul-Sabatier, Toulouse.
Presse Med. 2005 Jan 29;34(2 Pt 1):121-7. doi: 10.1016/s0755-4982(05)88242-9.
Calorie restriction increases longevity in rodents, delays the onset of certain diseases and has positive effects on ageing. Studies are ongoing in non-human primates. Eight persons following such a diet for 2 years reacted as anticipated (loss of body weight and fat, decrease in glycaemia and body temperature, etc.). Calorie restriction perhaps teaches us more on the means of resisting malnutrition than on ageing in normal dietary conditions. Calorie restriction is a tool for research, but it should not be recommended by practitioners, notably in elderly patients.
热量限制可延长啮齿动物的寿命,延缓某些疾病的发作,并对衰老有积极影响。针对非人类灵长类动物的研究正在进行中。八名遵循这种饮食方式两年的人出现了预期的反应(体重和脂肪减轻、血糖和体温下降等)。热量限制或许更多地教会我们抵抗营养不良的方法,而非正常饮食条件下的衰老方式。热量限制是一种研究工具,但从业者不应推荐它,尤其是针对老年患者。