Taube Tillmann, Schmid Hansjörg, Reinhard Harald, von Stackelberg Arend, Overberg Ursula Schulte
Haematologica. 2005 Feb;90(2):281-3.
Twenty-two children with immune thrombocytopenic purpura (ITP) with long-lasting thrombocytopenia, adversely affecting their quality of life, were treated with a reduced rituximab regimen in order to eliminate B cells producing anti-platelet antibody. A single dose of rituximab resulted in a response rate similar to that reported for cases in which 4 doses of rituximab were used.
22名患有免疫性血小板减少性紫癜（ITP）且长期血小板减少、生活质量受到不利影响的儿童，接受了减量利妥昔单抗方案治疗，以清除产生抗血小板抗体的B细胞。单剂量利妥昔单抗的缓解率与使用4剂利妥昔单抗的病例报告的缓解率相似。
