怀孕运动不足大鼠黄体的形态计量学变化
Morphometric changes in the corpus luteum of pregnant hypokinetic rats.
作者信息
Kujawa Marek, Ziemba Halina, Baran Wojciech
机构信息
Department of Histology and Embryology, Centre for Biostructure Research, Medical University, Warsaw, Poland.
出版信息
Folia Morphol (Warsz). 2004 Nov;63(4):413-7.
The aim of this work was to study the influence of hypokinetic conditions on the ovary and corpus luteum of pregnant rats. The rats were kept in hypokinetic conditions for 5 days in the period between the 13th and 18th days of pregnancy. A three-dimensional reconstruction of the ovary and corpora lutea and also a stereological evaluation of the luteal cells and their nuclei were performed using serially cut material. Hypokinesia caused a decrease in the mean volume of the ovary and individual corpus luteum and in the total volume of corpora lutea per ovary in immobilised animals as compared to the control. Moreover, a decrease was observed in the mean number of luteal cells and an increase in the size of these cells, as well as in the mean volume fraction of their nuclei. These results indicate that immobilisation of pregnant rats for 5 days considerably influences the morphology of the corpus luteum and luteal cells.
这项工作的目的是研究运动不足状态对妊娠大鼠卵巢和黄体的影响。在妊娠第13天至18天期间，将大鼠置于运动不足状态5天。使用连续切片材料对卵巢和黄体进行三维重建，并对黄体细胞及其细胞核进行体视学评估。与对照组相比，运动不足导致固定动物的卵巢平均体积、单个黄体平均体积以及每个卵巢黄体总体积减小。此外，观察到黄体细胞平均数量减少，这些细胞大小增加，以及其细胞核平均体积分数增加。这些结果表明，妊娠大鼠固定5天对黄体和黄体细胞的形态有显著影响。
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