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唾液替代产品治疗老年人口干症的有效性:一项试点研究。

Effectiveness of saliva substitute products in the treatment of dry mouth in the elderly: a pilot study.

作者信息

Matear David W, Barbaro John

机构信息

Clinical Affairs, Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada.

出版信息

J R Soc Promot Health. 2005 Jan;125(1):35-41. doi: 10.1177/146642400512500113.

Abstract

The aging population is susceptible to developing dry mouth (xerostomia). Elderly patients present all of the major risk factors to acquiring dry mouth which include systemic diseases and disorders, such as diabetes and depression, and the use of numerous medications, including anti-hypertensives and anti-depressants. The consequences of untreated dry mouth are severe limitations of masticatory function and speech, and increased risk of developing caries, periodontal diseases and fungal infections. Assessment of xerostomia, which includes a set of signs and symptoms that impact on the individual, can only be fully explored through a thorough medical history, intra-oral examination and recording the subjective views of patients. This study suggests a methodology for the assessment of xerostomia through a xerostomia questionnaire, which was used to evaluate the effectiveness and acceptability of a saliva substitute product (Biotène) in the treatment of xerostomia in 20 elderly patients exhibiting both severe and moderate symptoms. Wilcoxon signed-ranked tests revealed significant improvements in the number and severity of symptoms between the pre-test and the post-test groups. Biotène products were also found to be effective in the treatment of both severe and moderate symptoms of xerostomia. Biotène saliva substitutes are an acceptable and effective method of treatment for elderly people suffering from dry mouth.

摘要

老龄化人口易患口干症(口腔干燥)。老年患者存在引发口干症的所有主要风险因素,包括全身性疾病和失调,如糖尿病和抑郁症,以及使用多种药物,包括抗高血压药和抗抑郁药。未经治疗的口干症后果是咀嚼功能和言语严重受限,以及患龋齿、牙周疾病和真菌感染的风险增加。口干症的评估包括一系列影响个体的体征和症状,只有通过全面的病史、口腔内检查以及记录患者的主观意见才能充分探究。本研究提出了一种通过口干症问卷评估口干症的方法,该问卷用于评估一种唾液替代产品(保丽净)对20名有重度和中度症状的老年口干症患者的治疗效果和可接受性。威尔科克森符号秩检验显示,测试前组和测试后组在症状数量和严重程度上有显著改善。还发现保丽净产品对治疗重度和中度口干症症状均有效。保丽净唾液替代品是治疗老年口干症患者的一种可接受且有效的方法。

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