Khoshhal Khalid I, Kiefer Gerhard N
Department of Orthopedics, King Khalid University Hospital, Riyadh, Saudi Arabia.
J Am Acad Orthop Surg. 2005 Jan-Feb;13(1):47-58. doi: 10.5435/00124635-200501000-00007.
Growth arrest secondary to physeal bridge formation is an uncommon but well-recognized complication of physeal fractures and other injuries. Regardless of the underlying etiology, physeal bridges may cause angular and/or longitudinal growth disturbances, with progression dependent on the remaining physeal growth potential. Physeal bridge resection and insertion of interposition material releases the tethering effect of the bridge. Physeal bridge resection has become an accepted treatment option for patients with existing or developing deformity and for those with at least 2 years or 2 cm of growth remaining. Current experimental research is focused on the use of gene therapy and other factors that enhance chondrocyte proliferation to improve the management of growth arrest. The use of cartilage and cultured chondrocytes as interposition material after physeal bridge resection is an area of active research.
继发于骨骺桥形成的生长停滞是一种罕见但已得到充分认识的骨骺骨折及其他损伤的并发症。无论潜在病因如何，骨骺桥均可导致成角和/或纵向生长紊乱，其进展取决于剩余的骨骺生长潜力。骨骺桥切除及植入间隔材料可解除桥的束缚作用。对于已有或正在发展的畸形患者以及剩余生长时间至少2年或生长长度至少2厘米的患者，骨骺桥切除已成为一种可接受的治疗选择。当前的实验研究集中在基因治疗及其他促进软骨细胞增殖的因素的应用，以改善生长停滞的治疗。骨骺桥切除后使用软骨和培养的软骨细胞作为间隔材料是一个活跃的研究领域。
