Vouriot Alexandre, Gauchard Gérome C, Chau Nearkasen, Nadif Rachel, Mur Jean-Marie, Perrin Philippe P
National Institute for Health and Medical Research (INSERM), U420, Faculty of Medicine, Vandoeuvre-lès-Nancy, France.
Neurotoxicology. 2005 Mar;26(2):193-8. doi: 10.1016/j.neuro.2004.11.002.
Exposure to anesthetic gases is known to alter certain structures and functions of the central nervous system. As the effects of long-term exposure on balance control mechanisms have been the subject of few investigations, these were evaluated in 53 operating room personnel exposed to anesthetic gases and in 53 non-exposed individuals. Balance control was assessed by static and dynamic posturography. Exposed workers had the worst static and dynamic postural performances, particularly in the eyes closed condition, suggesting increased dependency on vision and decreased use of proprioception. This poorer ability to modify the weight and to switch the different cues controlling balance suggests central information processing disorders. By impairing information and its central integration, exposure to anesthetics gases leads to inappropriate organization of sensorimotor stabilization strategies.
已知接触麻醉气体会改变中枢神经系统的某些结构和功能。由于长期接触对平衡控制机制的影响鲜有研究,因此对53名接触麻醉气体的手术室工作人员和53名未接触者进行了评估。通过静态和动态姿势描记法评估平衡控制。接触麻醉气体的工作人员静态和动态姿势表现最差,尤其是在闭眼状态下,这表明他们对视觉的依赖增加,本体感觉的使用减少。这种改变体重和切换控制平衡的不同线索的能力较差表明存在中枢信息处理障碍。接触麻醉气体通过损害信息及其中枢整合,导致感觉运动稳定策略的组织不当。