Robinson A J, Mercey D E, Preston M, Bingham J S
Department of Genitourinary Medicine, University College Hospital, London, UK.
Int J STD AIDS. 1992 Mar-Apr;3(2):123-4. doi: 10.1177/095646249200300209.
The prognostic implications of minor grades of abnormality on cervical cytology are unclear. Women attending genitourinary medicine clinics who had cytology showing inflammatory changes with or without koilocytosis or borderline dyskaryosis have a high incidence of cervical intraepithelial neoplasia and genital infection. Of 119 patients who had a colposcopically directed cervical biopsy after one smear showing these changes, 46 (38%) had cervical intraepithelial neoplasia. Seventy-eight (57%) of 138 women had genital infection of whom 26 (33%) had a sexually transmitted disease. We recommend vigilant follow-up of borderline cytology including colposcopy if adequate facilities exist.
宫颈细胞学检查中轻度异常的预后意义尚不清楚。在泌尿生殖医学门诊就诊且细胞学检查显示有炎症改变（伴或不伴挖空细胞或临界核异质）的女性，宫颈上皮内瘤变和生殖器感染的发生率较高。在119例一次涂片显示上述改变后接受阴道镜引导下宫颈活检的患者中，46例（38%）有宫颈上皮内瘤变。138名女性中有78例（57%）有生殖器感染，其中26例（33%）患有性传播疾病。我们建议对临界细胞学检查进行密切随访，如有足够的设备，可进行阴道镜检查。
