Munshi Sunil K, Thanvi Bhomraj, Chin Su Kiun, Hubbard Irene, Fletcher Alan, Vallance Tony R
Department of Cerebrovascular Medicine & Medicine for the Elderly, Leicester General Hospital, University Hospital of Leicester, Gwendolen Road, Leicester LE5 4PW, UK.
Age Ageing. 2005 Mar;34(2):190-3. doi: 10.1093/ageing/afi017.
We report a 77-year old man who presented with a sub-acute dementia associated with aggressive behaviour, ataxia, rapid progression and death. No cause for his illness could be detected in his lifetime, but at post mortem he was found to have paraneoplastic limbic encephalitis and a bronchogenic tumour. A diagnosis of paraneoplastic limbic encephalitis should be considered in the differential diagnosis of unexplained dementias and appropriate investigations performed to diagnose the condition.
我们报告了一名77岁男性,他出现了与攻击性行为、共济失调、病情快速进展及死亡相关的亚急性痴呆。在其生前未检测到病因,但尸检时发现他患有副肿瘤性边缘叶脑炎和支气管源性肿瘤。在不明原因痴呆的鉴别诊断中应考虑副肿瘤性边缘叶脑炎的诊断,并进行适当检查以诊断该病。