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副肿瘤性边缘叶脑炎——病例报告及文献综述

Paraneoplastic limbic encephalitis--case report and review of literature.

作者信息

Munshi Sunil K, Thanvi Bhomraj, Chin Su Kiun, Hubbard Irene, Fletcher Alan, Vallance Tony R

机构信息

Department of Cerebrovascular Medicine & Medicine for the Elderly, Leicester General Hospital, University Hospital of Leicester, Gwendolen Road, Leicester LE5 4PW, UK.

出版信息

Age Ageing. 2005 Mar;34(2):190-3. doi: 10.1093/ageing/afi017.

DOI:10.1093/ageing/afi017
PMID:15713869
Abstract

We report a 77-year old man who presented with a sub-acute dementia associated with aggressive behaviour, ataxia, rapid progression and death. No cause for his illness could be detected in his lifetime, but at post mortem he was found to have paraneoplastic limbic encephalitis and a bronchogenic tumour. A diagnosis of paraneoplastic limbic encephalitis should be considered in the differential diagnosis of unexplained dementias and appropriate investigations performed to diagnose the condition.

摘要

我们报告了一名77岁男性,他出现了与攻击性行为、共济失调、病情快速进展及死亡相关的亚急性痴呆。在其生前未检测到病因,但尸检时发现他患有副肿瘤性边缘叶脑炎和支气管源性肿瘤。在不明原因痴呆的鉴别诊断中应考虑副肿瘤性边缘叶脑炎的诊断,并进行适当检查以诊断该病。

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1
Paraneoplastic limbic encephalitis--case report and review of literature.副肿瘤性边缘叶脑炎——病例报告及文献综述
Age Ageing. 2005 Mar;34(2):190-3. doi: 10.1093/ageing/afi017.
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[Partial non convulsive epileptic status as initial presentation of limbic encephalitis].[部分性非惊厥性癫痫持续状态作为边缘叶脑炎的首发表现]
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[Limbic encephalitis].
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Paraneoplastic limbic encephalitis associated with bronchogenic carcinoma: a case report.与支气管源性癌相关的副肿瘤性边缘叶脑炎:一例报告
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[Paraneoplastic limbic encephalitis with positive anti-RI antibodies and mediastinal seminoma].伴抗-RI抗体阳性及纵隔精原细胞瘤的副肿瘤性边缘叶脑炎
Rev Neurol (Paris). 2008 Jun-Jul;164(6-7):612-9. doi: 10.1016/j.neurol.2008.02.044. Epub 2008 May 13.
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[A case of paraneoplastic limbic encephalitis in autoptic occult primary malignancy].
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[Schizophreniform psychosis in paraneoplastic limbic encephalitis].
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Anti-Hu-associated paraneoplastic limbic encephalitis presenting as rapidly progressive non-convulsive status epilepticus.以快速进展性非惊厥性癫痫持续状态为表现的抗Hu相关副肿瘤性边缘叶脑炎。
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Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-1988. A 76-year-old man with confusion, agitation, and a gait disorder.马萨诸塞州总医院病例记录。每周临床病理讨论。病例39 - 1988。一名76岁男性,伴有意识模糊、烦躁不安和步态障碍。
N Engl J Med. 1988 Sep 29;319(13):849-60. doi: 10.1056/NEJM198809293191308.

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Leucine-Rich Glioma-Inactivated Protein 1 Antibody-Positive Limbic Encephalitis in a Patient with Adenocarcinoma of Prostate: A Case Report.前列腺腺癌患者的富含亮氨酸胶质瘤失活蛋白1抗体阳性边缘叶脑炎:一例报告
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An emerging problem in clinical practice: how to approach acute psychosis.
临床实践中一个新出现的问题:如何处理急性精神病。
Clin Pract. 2011 Dec 30;2(1):e7. doi: 10.4081/cp.2012.e7. eCollection 2012 Jan 1.
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Paraneoplastic limbic encephalitis as a cause of new onset of seizures in a patient with non-small cell lung carcinoma: a case report.副肿瘤性边缘叶脑炎作为非小细胞肺癌患者新发癫痫发作的病因:一例报告
J Med Case Rep. 2008 Aug 13;2:270. doi: 10.1186/1752-1947-2-270.