Ficarra G, Shillitoe E J
Institute of Odontology and Stomatology, University of Florence, Italy.
Crit Rev Oral Biol Med. 1992;3(3):207-31. doi: 10.1177/10454411920030030301.
Oral infections are among the first manifestations of infection by the human immunodeficiency virus (HIV). They include fungal, viral, and bacterial infections and range from being essentially trivial, through troublesome to life threatening. Although some infections are due to overproliferation of the normal oral flora, others are due to organisms that normally are not found in the mouth. The clinical features of many of these infections have now been characterized, and clinical trials have indicated the optimal management. However, for many infections, the underlying processes are still not clear, and improvements in treatment are necessary.
口腔感染是人类免疫缺陷病毒(HIV)感染的首批表现之一。它们包括真菌、病毒和细菌感染,范围从基本无害到麻烦棘手乃至危及生命。尽管有些感染是由于口腔正常菌群过度增殖所致,但其他感染则是由口腔中通常不存在的微生物引起的。现在已经明确了其中许多感染的临床特征,临床试验也表明了最佳治疗方法。然而,对于许多感染来说,其潜在机制仍不明确,因此有必要改进治疗方法。