Yang Cheng, Zhu Ji-xiao, Wang Yin, Wen Yao-lin, Kong Ling-dong
State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing 210093, China.
Zhongguo Zhong Yao Za Zhi. 2005 Jan;30(2):145-8.
To investigate the effects of processing Phellodendron anurene with salt on anti-gout.
The mouse serum uric acid level and liver xanthine oxidase activity were used to evaluate anti-gout effects of raw and processing P. amurense with salt.
Both raw and processing P. amurense with salt reduced serum uric acid levels in the in hyperuricemic mice, and inhibited activities of liver xanthine oxidase at the low and high doses respectively, thus exhibiting anti-gout effects. Moreover, they showed the tendency to decrease the uric acid levels in the normal animal only at the high dose. The latter was a little weaker than the former.
Processing with salt might not significantly change anti-gout effect of P. amurense.
研究盐炙黄柏的抗痛风作用。
采用小鼠血清尿酸水平和肝脏黄嘌呤氧化酶活性来评价生黄柏和盐炙黄柏的抗痛风作用。
生黄柏和盐炙黄柏均可降低高尿酸血症小鼠的血清尿酸水平，且分别在低剂量和高剂量时抑制肝脏黄嘌呤氧化酶的活性，从而发挥抗痛风作用。此外，二者仅在高剂量时显示出降低正常动物尿酸水平的趋势，后者作用稍弱于前者。
盐炙可能不会显著改变黄柏的抗痛风作用。
