Zhao Qing-Zhen, Zhao Shuang-Yi, Xia Guang-Min
College of Life Science, Shandong University, Jinan 250100, China.
Yi Chuan Xue Bao. 2005 Jan;32(1):104-10.
RNA silencing is a supervising mechanism in eukaryote which can prevent virus duplication, repress transposition of transposon and regulate gene expression. Compared with that in animals, RNA silencing in plants shows some differences in the function of RdRP, in bi-directional transitive RNAi, and in systemic propagation, etc. Meanwhile,the endogenous small RNAs in plants are more diverse than those in animals. In this paper, it is reviewed of the mechanism of RNA silencing in plants and the possibility of its use in plant functional Genomics.
RNA沉默是真核生物中的一种监控机制，它可以阻止病毒复制、抑制转座子转座并调节基因表达。与动物中的RNA沉默相比，植物中的RNA沉默在RNA依赖的RNA聚合酶（RdRP）功能、双向传递RNA干扰以及系统传播等方面存在一些差异。同时，植物中的内源性小RNA比动物中的更加多样。本文综述了植物中RNA沉默的机制及其在植物功能基因组学中的应用可能性。
