Croghan Anne, Heitkemper Margaret M
Seattle Gastroenterology Associates, Seattle, Washington, USA.
J Am Acad Nurse Pract. 2005 Feb;17(2):51-9. doi: 10.1111/j.1041-2972.2005.00011.x.
To address the diagnosis and clinical management of irritable bowel syndrome (IBS) and provide a discussion of the available serotonergic agents.
Recent studies examining the pathophysiology of IBS.
Diagnostic testing may be required in the subset of patients with IBS who present with alarm symptoms, or "red flags," suggestive of underlying organic disease. An important role has been suggested for the neurotransmitter serotonin in both gut motility and visceral pain sensitivity.
A diagnosis of IBS is largely based on symptoms; therefore, effective clinician-patient communication and careful attention to details of patient presentation, history, and physical examination are essential.
探讨肠易激综合征（IBS）的诊断及临床管理，并讨论现有的5-羟色胺能药物。
近期关于IBS病理生理学的研究。
对于出现提示潜在器质性疾病的报警症状或“红旗征”的IBS患者亚组，可能需要进行诊断性检查。神经递质5-羟色胺在肠道动力和内脏疼痛敏感性方面均发挥重要作用。
IBS的诊断很大程度上基于症状；因此，有效的医患沟通以及对患者表现、病史和体格检查细节的仔细关注至关重要。
