MMWR Morb Mortal Wkly Rep. 2005 Feb 18;54(6):149-52.
In 2003, the incidence of tuberculosis (TB) cases in the United States declined for the eleventh consecutive year to a record low of 5.1 cases per 100,000 population. In 2003, 6.3% of reported TB cases in the United States were among homeless persons. Compared with the general population, this group has a greater risk for latent TB infection (LTBI) and progression to active disease. This report summarizes a recent outbreak of TB and highlights the challenges of preventing TB among homeless persons, particularly when multiple chains of transmission are occurring and multiple jurisdictions are involved. The findings underscore the complementary role of rapid DNA genotyping in the detection of possible TB transmission in homeless populations. To ensure early detection of unsuspected TB transmission in homeless populations, health department TB-control programs are encouraged to use CDC's universal Mycobacterium tuberculosis rapid genotyping system.
2003年,美国结核病(TB)病例发病率连续第十一年下降,降至每10万人口5.1例的历史最低点。2003年,美国报告的结核病病例中有6.3%是无家可归者。与普通人群相比,这一群体潜伏性结核感染(LTBI)及进展为活动性疾病的风险更高。本报告总结了近期的一次结核病暴发,并强调了在无家可归者中预防结核病的挑战,尤其是在出现多条传播链且涉及多个辖区时。这些发现强调了快速DNA基因分型在检测无家可归人群中可能的结核病传播方面的补充作用。为确保早期发现无家可归人群中未被怀疑的结核病传播,鼓励卫生部门的结核病控制项目使用美国疾病控制与预防中心(CDC)的通用结核分枝杆菌快速基因分型系统。