Miniero Roberto, Tardivo Irene, Curtoni Emilio Sergio, Bresadola Fabrizio, Calconi Gilberto, Cavallari Antonino, Centofanti Paolo, Filipponi Franco, Franchello Alessandro, Goggi Claudio, La Rocca Ennio, Mammana Carmelo, Nino Antonio, Parisi Francesco, Regalia Enrico, Rosati Alberto, Segoloni Giuseppe Paolo, Setti Gisella, Todeschini Paola, Tregnaghi Carla, Zanelli Paola, Dall'Omo Anna Maria
Department Of Paediatrics, University of Turin, Ospedale San Luigi di Orbassano, Reg. Gonzole 10, 10043, Orbassano, Italy.
Transpl Int. 2005 Jan;17(11):724-9. doi: 10.1007/s00147-004-0781-9. Epub 2004 Nov 26.
The number of women who decide to have a child after organ transplantation has increased. We determined the outcomes of 67 pregnancies of women who had undergone kidney, liver or heart transplantation. All recipients had been maintained on immunosuppressive therapy before and during pregnancy. Pregnancy complications at term were observed in 17 out of 67 women (25%), hypertension being the most frequent complication (16.17%). Two transplant rejections were reported. Sixty-eight infants were delivered (including one pair of twins); five women had two pregnancies at term. Twenty-eight miscarriages (29.2%) were recorded. Of these 68 babies (including the pair of twins), 40 (58.8%) were born at term and 28 (41.2%) before term. The babies were followed-up for 2 months to 13 years. According to our previous experience, our study shows that patients who have undergone organ transplantation can give birth to healthy infants as long as they are monitored accurately during pregnancy.
决定在器官移植后生育的女性数量有所增加。我们确定了67例接受过肾脏、肝脏或心脏移植的女性的妊娠结局。所有受者在妊娠前和妊娠期间均接受免疫抑制治疗。67名女性中有17名（25%）在足月时出现妊娠并发症，高血压是最常见的并发症（16.17%）。报告了2例移植排斥反应。共分娩68名婴儿（包括一对双胞胎）；5名女性足月妊娠2次。记录到28次流产（29.2%）。在这68名婴儿（包括双胞胎）中，40名（58.8%）足月出生，28名（41.2%）早产。对这些婴儿进行了2个月至13年的随访。根据我们之前的经验，我们的研究表明，接受过器官移植的患者只要在孕期得到准确监测，就能够生下健康的婴儿。
