Liptak Julius M, Pluhar G Elizabeth, Dernell William S, Withrow Stephen J
Animal Cancer Center and Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Vet Surg. 2005 Jan-Feb;34(1):71-7. doi: 10.1111/j.1532-950X.2005.00013.x.
To report successful limb-sparing surgery in a dog with a proximal femoral osteosarcoma (OSA) using a composite allograft-prosthetic technique.
Case report.
Client-owned dog.
A stage IIB OSA of the proximal aspect of the femur was resected in accordance with oncologic and limb-sparing principles. The osseous defect was reconstructed with a proximal femoral allograft and cemented, long-stemmed femoral prosthesis. Soft tissue reconstruction was achieved by suturing host tendons to their respective allogeneic tendons on the allograft. Coxofemoral joint function was preserved using standard total hip arthroplasty techniques.
Limb-sparing surgery of the proximal aspect of the femur using a composite allograft-prosthetic technique resulted in excellent limb function. Postoperative complications included aseptic loosening of the femoral composite graft and allograft nonunion, which required revision, traumatic implant luxation, and local tumor recurrence. Limb function was excellent after surgical stabilization of the allograft nonunion but deteriorated after implant luxation 270 days postlimb-sparing surgery. Pulmonary and skeletal metastases were diagnosed and local tumor recurrence suspected 596 and 650 days postoperatively, respectively. The dog was euthanatized 688 days after limb-sparing surgery as a result of progressive local and metastatic disease.
Limb-sparing surgery for dogs with primary bone tumors of the proximal aspect of the femur is feasible with good functional results.
报告采用同种异体移植-假体复合技术对一只患有股骨近端骨肉瘤（OSA）的犬成功实施保肢手术。
病例报告。
一只客户拥有的犬。
根据肿瘤学和保肢原则，切除股骨近端IIB期骨肉瘤。采用股骨近端同种异体骨移植并使用骨水泥固定长柄股骨假体来重建骨缺损。通过将宿主肌腱缝合到同种异体骨上各自的同种异体肌腱来实现软组织重建。使用标准全髋关节置换技术保留髋关节功能。
采用同种异体移植-假体复合技术对股骨近端进行保肢手术，肢体功能良好。术后并发症包括股骨复合移植物无菌性松动和同种异体骨不愈合（需要翻修）、创伤性植入物脱位以及局部肿瘤复发。同种异体骨不愈合经手术稳定后肢体功能良好，但在保肢手术后270天植入物脱位后功能恶化。术后596天和650天分别诊断出肺转移和骨转移，并怀疑局部肿瘤复发。由于局部和转移性疾病进展，该犬在保肢手术后688天实施安乐死。
对患有股骨近端原发性骨肿瘤的犬进行保肢手术是可行的，功能效果良好。
