Spencer J, Thomas S R Y W, Yardy G, Mukundan C, Barrington R
Department of Orthopaedics, Kettering General Hospital, Northamptonshire, UK.
Ann R Coll Surg Engl. 2005 Jan;87(1):28-30. doi: 10.1308/1478708051379.
To determine the proportion of patients who received a blood transfusion after joint replacement, and to devise a simple method to ensure patients were transfused based on strict clinical and haematological need.
Prospective audit over 2 years.
The study group was 151 patients who underwent total hip and knee arthroplasty in a typical district general hospital (Kettering) over a 2-year period. They were divided into three consecutive groups. Current practice was audited (producing the first group of 62 patients) and transfusion rates were compared to regional figures. Local guidelines were drawn up. A form was introduced on which the indications for any transfusion had to be documented prior to transfusion of the blood. This was designed to encourage transfusion only on strong clinical grounds or an haemoglobin (Hb) level < 8 g/dl. Transfusion practice was then re-audited (producing the second group of 44 patients) to assess whether practice had improved. A year later, all relevant staff were reminded by letter of the guidelines. The process was then re-audited (producing the third group of 45 patients) again to determine whether practice remained improved or not.
In the first audit (current practice) of 62 patients, the overall transfusion rate was 71%, with a higher rate in the hip replacement group (84%) ordered mainly by anaesthetic staff. Ward staff were reluctant not to transfuse patients whose Hb level fell below 10 g/dl. In the second audit, the transfusion rate fell by nearly 50% to 37%, with almost identical figures for knee and hip replacement. In the third audit of 45 patients, a year later, the transfusion rate was 40% overall.
Patients were being transfused routinely, generally without good clinical evidence of benefit to the patient. The audit process was successful in instituting change for the better in blood transfusion practice for elective joint replacement. The improved practice can be largely maintained provided staff are regularly reminded of appropriate guidelines and encouraged to transfuse for clinical need only. For absolute adherence to guidelines, we would recommend a compulsory form system be introduced for transfusion in the per-operative period, to ensure blood transfusion is only given when absolutely necessary.
确定关节置换术后接受输血的患者比例,并设计一种简单方法,以确保患者根据严格的临床和血液学需求接受输血。
为期2年的前瞻性审计。
研究组为151例在一家典型的地区综合医院(凯特林医院)接受全髋关节和膝关节置换术的患者,时间跨度为2年。他们被连续分为三组。对当前的做法进行审计(产生第一组62例患者),并将输血率与地区数据进行比较。制定了当地指南。引入了一种表格,要求在输血前必须记录任何输血的指征。这旨在鼓励仅在有充分临床依据或血红蛋白(Hb)水平<8 g/dl时进行输血。然后对输血做法进行重新审计(产生第二组44例患者),以评估做法是否有所改善。一年后,通过信件提醒所有相关工作人员注意这些指南。然后再次对该过程进行重新审计(产生第三组45例患者),以确定做法是否仍然保持改善。
在对62例患者的首次审计(当前做法)中,总体输血率为71%,髋关节置换组的输血率更高(84%),主要由麻醉人员要求输血。病房工作人员不愿意不给Hb水平降至10 g/dl以下的患者输血。在第二次审计中,输血率下降了近50%,降至37%,膝关节和髋关节置换的数字几乎相同。在一年后的第三次对45例患者的审计中,总体输血率为40%。
患者通常在没有对患者有益的良好临床证据的情况下常规接受输血。审计过程成功地使择期关节置换的输血做法得到了改善。只要定期提醒工作人员注意适当的指南,并鼓励他们仅根据临床需求进行输血,这种改进的做法在很大程度上可以维持。为了绝对遵守指南,我们建议在手术期间引入强制性的输血表格系统,以确保仅在绝对必要时才进行输血。