Evatt Bruce L
Curr Hematol Rep. 2005 Mar;4(2):149-53.
Thrombocytopenia is a common complication of HIV infection. The low platelet count can be caused by multiple mechanisms including immune-mediated destruction, decreased platelet production, effects of drugs on progenitors, or by the development of a form of thrombotic thrombocytopenic purpura (TTP). Bleeding problems associated with the thrombocytopenia can be accentuated by the presence of platelet dysfunction produced by drugs used to treat HIV/AIDs or its complications. Therapy should be directed at reducing the load of the HIV virus of the patient supplemented by other therapies chosen depending on the specific underlying cause.
血小板减少是HIV感染的常见并发症。血小板计数低可由多种机制引起，包括免疫介导的破坏、血小板生成减少、药物对祖细胞的影响，或血栓性血小板减少性紫癜（TTP）的发生。用于治疗HIV/AIDS或其并发症的药物所产生的血小板功能障碍会加重与血小板减少相关的出血问题。治疗应旨在降低患者体内HIV病毒的负荷，并根据具体潜在病因辅以其他治疗方法。
