Goulding Martyn, Pfaff Samuel L
Molecular Neurobiology Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Curr Opin Neurobiol. 2005 Feb;15(1):14-20. doi: 10.1016/j.conb.2005.01.017.
Neurobiologists have long sought to understand how circuits in the nervous system are organized to generate the precise neural outputs that underlie particular behaviors. Given the complexity of the nervous system in higher vertebrates this is a daunting task. Nevertheless, recent advances in developmental genetics hold out hope that studies of locomotor and respiratory circuits will provide general insight for understanding how ensembles of neurons are wired to control specific behaviors.
神经生物学家长期以来一直试图了解神经系统中的回路是如何组织起来,以产生构成特定行为基础的精确神经输出的。鉴于高等脊椎动物神经系统的复杂性,这是一项艰巨的任务。尽管如此,发育遗传学的最新进展让人看到希望,即对运动和呼吸回路的研究将为理解神经元群如何连接以控制特定行为提供一般性的见解。