Tutuian Radu, Castell Donald O
Division of Gastroenterology/Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA.
Gastrointest Endosc Clin N Am. 2005 Apr;15(2):361-71. doi: 10.1016/j.giec.2004.10.002.
Combined multichannel intraluminal impedance and pH (MII-pH) is a promising technique that identifies liquid, gas, and mixed gastroesophageal reflux and categorizes it into acid and nonacid types. Gastroesophageal monitoring using combined MII-pH reconfirms previously reported data that there is a difference between refluxate volume presence time in the esophagus and time pH less than 4. Only one in five patients with persistent symptoms on acid-suppressive therapy have symptoms associated with persistent acid reflux, whereas two of five patients have symptoms associated with nonacid reflux; the remaining patients do not have any type of GER related to their symptoms. Combined MII-pH is a useful tool in evaluating patients with persistent symptoms on acid-suppressive therapy, patients with atypical symptoms, and infants.
联合多通道腔内阻抗和pH值监测（MII-pH）是一项很有前景的技术，它能够识别液体、气体及混合性胃食管反流，并将其分为酸性和非酸性类型。使用联合MII-pH进行胃食管监测再次证实了先前报道的数据，即食管内反流物的体积存在时间与pH值小于4的时间存在差异。在接受抑酸治疗后仍有持续症状的患者中，只有五分之一的患者症状与持续性酸性反流有关，而五分之二的患者症状与非酸性反流有关；其余患者的症状与任何类型的胃食管反流均无关。联合MII-pH是评估接受抑酸治疗后仍有持续症状的患者、有非典型症状的患者及婴儿的有用工具。
