高剂量玻璃体内注射曲安奈德治疗成人科茨综合征的严重黄斑水肿消退情况
Resolution of severe macular oedema in adult Coat's syndrome with high-dose intravitreal triamcinolone acetonide.
作者信息
Jarin R R, Teoh S C B, Lim T H
机构信息
The Eye Institute, Tan Tock Seng Hospital, Singapore, Republic of Singapore.
出版信息
Eye (Lond). 2006 Feb;20(2):163-5. doi: 10.1038/sj.eye.6701828.
OBJECTIVE
To report the clinical outcome of a patient who received high-dose intravitreal triamcinolone acetonide as treatment for severe macular oedema secondary to adult Coat's syndrome.
METHOD
Case report.
RESULTS
A 74-year-old Indian man complaining of chronic gradual blurring of vision in the left eye was found to have adult Coat's syndrome with severe macular oedema. He received 25 mg of intravitreal triamcinolone acetonide following unsuccessful resolution with grid laser. Optical coherence tomography (OCT) demonstrated up to 75% decrease in macular oedema that was evident even after 9 months follow-up. However, there was no significant improvement in visual acuity.
CONCLUSION
Intravitreal triamcinolone is a reasonable option in reducing severe macular oedema in cases of adult Coat's syndrome.
目的
报告1例接受高剂量玻璃体内注射曲安奈德治疗成人Coats综合征继发严重黄斑水肿的患者的临床结局。
方法
病例报告。
结果
一名74岁印度男性因左眼慢性渐进性视力模糊就诊，被诊断为成人Coats综合征伴严重黄斑水肿。在格栅激光治疗未成功后，他接受了25mg玻璃体内注射曲安奈德。光学相干断层扫描（OCT）显示黄斑水肿减轻达75%，即使在随访9个月后仍很明显。然而，视力没有显著改善。
结论
玻璃体内注射曲安奈德是减少成人Coats综合征患者严重黄斑水肿的合理选择。
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