Hunter Alasdair G W
529 Clarence St East, Ottawa, Ontario, Canada.
Am J Med Genet A. 2005 Apr 30;134(3):237-9. doi: 10.1002/ajmg.a.30619.
This study describes the course of a clinical trial designed to investigate the possible role of thrombophilic factors in limb reduction defects, which was abandoned after 1 year because lack of progress of the project through ethics review and the failure to make significant inroads in patient recruitment. Factors that are thought to have contributed to the failure are discussed, in the hope that others can avoid some of the pitfalls.
本研究描述了一项旨在调查血栓形成倾向因素在肢体减少缺陷中可能作用的临床试验过程，该试验在1年后因项目在伦理审查中缺乏进展以及未能在患者招募方面取得重大进展而被放弃。文中讨论了被认为导致失败的因素，希望其他人能够避免一些陷阱。
