Dreher Alfred, de la Chaux Richard, Klemens Christine, Werner Robert, Baker Fiona, Barthlen Gabriele, Rasp Gerd
Department of Otorhinolaryngology, Ludwig-Maximilians-University, Munich, Germany.
Arch Otolaryngol Head Neck Surg. 2005 Feb;131(2):95-8. doi: 10.1001/archotol.131.2.95.
To examine whether medical history and nasopharyngeal examination are useful for predicting obstructive sleep apnea syndrome (OSAS) and to compare these findings with those of the gold standard, polysomnography.
Patients underwent polysomnography recordings for 2 nights and an otorhinolaryngologic examination, including flexible endoscopy and the Muller maneuver. Nasal and pharyngeal findings were scored in a semiquantitative way. The medical history of each patient was taken using a standardized questionnaire. Anatomic and functional findings and patient history were correlated with the mean apnea-hypopnea index (AHI).
An otorhinolaryngologic clinic.
A total of 101 patients presenting with a primary complaint of snoring.
Differences between patients with OSAS and primary snorers were assessed using the Mann-Whitney test (anatomic findings), t test (Muller maneuver), and chi(2) test after Pearson correlation (questionnaire). P values less than .05 were considered statistically significant.
The mean +/- SD AHI of the patients was 19.7 +/- 21.5); 52 patients had an AHI higher than 10, which confirmed the diagnosis of OSAS. These patients tended to report the occurrence of apneas more frequently than patients with an AHI of 10 or lower. The average ranks (Mann-Whitney findings) of patients with AHIs higher than 10 vs those with AHIs of 10 or lower were 52 vs 50 for septal deviation; 50 vs 52 for tonsil size; 53 vs 49 for low velum level; and 56 vs 46 for hyperplasia of the tongue base. None of these differences reached statistical significance. Mean +/- SD narrowing of the airway during the Müller maneuver was significantly (P<.05) more pronounced in patients with an AHI higher than 10 than in patients with an AHI of 10 or lower at the levels of the velum (80% +/- 20% vs 68% +/- 30%) and the tongue base (57% +/- 24% vs 44% +/- 27%).
None of the reported medical history and/or anatomic parameters alone or in combination could be used to distinguish patients with OSAS from snoring patients. Snoring patients, therefore, should be examined at least by a nocturnal screening test for OSAS before any therapeutic decision is made.
探讨病史及鼻咽部检查对预测阻塞性睡眠呼吸暂停综合征(OSAS)是否有用,并将这些结果与金标准多导睡眠图的结果进行比较。
患者接受两晚的多导睡眠图记录及耳鼻咽喉科检查,包括纤维内镜检查和米勒动作。对鼻和咽的检查结果进行半定量评分。使用标准化问卷获取每位患者的病史。将解剖学和功能学检查结果及患者病史与平均呼吸暂停低通气指数(AHI)进行关联分析。
一家耳鼻咽喉科诊所。
共有101例以打鼾为主诉的患者。
采用曼-惠特尼检验(解剖学检查结果)、t检验(米勒动作)以及皮尔逊相关分析后的卡方检验(问卷)评估OSAS患者与原发性打鼾者之间的差异。P值小于0.05被认为具有统计学意义。
患者的平均±标准差AHI为19.7±21.5;52例患者的AHI高于10,确诊为OSAS。这些患者比AHI为10或更低的患者更倾向于频繁报告呼吸暂停的发生。AHI高于10的患者与AHI为10或更低的患者相比,鼻中隔偏曲的平均秩次(曼-惠特尼检验结果)分别为52和50;扁桃体大小分别为50和52;软腭水平分别为53和49;舌根增生分别为56和46。这些差异均未达到统计学意义。在米勒动作过程中,AHI高于10的患者气道平均±标准差狭窄程度在软腭水平(80%±20%对68%±30%)和舌根水平(57%±24%对44%±27%)显著(P<0.05)高于AHI为10或更低的患者。
所报告的病史和/或解剖学参数单独或联合使用均不能用于区分OSAS患者与打鼾患者。因此,在做出任何治疗决策之前,打鼾患者至少应接受一次OSAS的夜间筛查测试。