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急性咳嗽的管理:比利时和荷兰全科医生的比较

Management of acute cough: comparisons between Belgian and Dutch GPs.

作者信息

Coenen Samuel, Welschen Ineke, Van Royen Paul, Kuyvenhoven Marijke M, Denekens Joke, Verheij Theo J M

机构信息

Centre for General Practice, University of Antwerp, BE 2610 Antwerp, Belgium.

出版信息

Eur J Gen Pract. 2004 Dec;10(4):152-6. doi: 10.3109/13814780409044303.

Abstract

OBJECTIVES

In Europe there are large variations in overall outpatient antibiotic use, even between two neighbouring countries as Belgium and the Netherlands. We aimed to compare the management of acute cough between Belgian and Dutch general practitioners (GPs).

METHODS

In cross-sectional studies in Belgium and the Netherlands, 71 Belgian and 84 Dutch GPs included adult patients consulting for acute cough. Differences in antibiotic prescription rates, the percentage of first-choice antibiotics (i.e. tetracyclines and broad-spectrum penicillins) and bronchodilator prescription rates were assessed by using Generalised Estimates Equations to adjust for clustering of patients within GPs.

RESULTS

In Belgium 324/810 patients (40%) were prescribed an antibiotic compared with 101/309 (33%) in the Netherlands (adjusted OR (95% CI) 1.28 (0.91-1.83)). Belgian GPs prescribed fewer first-choice antibiotics compared with Dutch GPs: 124/324 (38%) versus 67/101 (66%) (adjusted OR (95% CI) 0.39 (0.22-0.72)). In both countries, 17% of the patients were prescribed a bronchodilator.

CONCLUSIONS

Antibiotic prescription rates for adult patients with acute cough were not significantly higher in Belgian than in Dutch general practice at the 5% significance level. Dutch GPs' antibiotic prescriptions were more in line with national guidelines. Bronchodilator prescription rates were similar. Because Dutch GPs probably encountered more severe cases of acute cough compared with their Belgian colleagues, the observed prescribing differences might be underestimated.

摘要

目的

在欧洲,门诊抗生素的总体使用情况存在很大差异,即使在比利时和荷兰这两个邻国之间也是如此。我们旨在比较比利时和荷兰全科医生(GP)对急性咳嗽的治疗方法。

方法

在比利时和荷兰进行的横断面研究中,71名比利时全科医生和84名荷兰全科医生纳入了因急性咳嗽前来就诊的成年患者。通过使用广义估计方程来调整全科医生内部患者的聚类情况,评估抗生素处方率、首选抗生素(即四环素和广谱青霉素)的百分比以及支气管扩张剂处方率的差异。

结果

在比利时,324/810名患者(40%)被开具了抗生素,而在荷兰这一比例为101/309(33%)(调整后的比值比(95%置信区间)为1.28(0.91 - 1.83))。与荷兰全科医生相比,比利时全科医生开具的首选抗生素较少:124/324(38%)对67/101(66%)(调整后的比值比(95%置信区间)为0.39(0.22 - 0.72))。在两个国家,均有17%的患者被开具了支气管扩张剂。

结论

在5%的显著性水平上,比利时成年急性咳嗽患者的抗生素处方率并不显著高于荷兰的全科医疗。荷兰全科医生的抗生素处方更符合国家指南。支气管扩张剂处方率相似。由于与比利时同行相比,荷兰全科医生可能遇到的急性咳嗽严重病例更多,所以观察到的处方差异可能被低估了。

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