Itthagarun Anut, Tay Franklin R, Pashley David H, Wefel James S, García-Godoy Franklin, Wei Stephen H Y
Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Am J Dent. 2004 Dec;17(6):394-400.
To test the hypothesis that formation of inhibition zones by bonded restorations in artificially-induced carious dentin lesions is related to the permeability of the self-etch adhesives.
Fluid conductance of four single-step self-etch adhesives (Prompt L-Pop, Etch&Prime 3.0, One-Up Bond F and Reactmer Bond), and a control two-step self-etch adhesive (UniFil Bond) were measured after sound dentin surfaces were:(1) acid-etched; (2) polished to produce smear layers; (3) bonded with the adhesive; each at 20 cm hydrostatic pressure (hp). Osmotic fluid conductance was also determined for the bonded dentin after immersion in 4.8 M CaCl2 at 0 cm hp. For artificial caries inhibition, a non-fluoride releasing (NFR) two-step self-etch adhesive (UniFil Bond) and a fluoride-releasing (FR) single-step adhesive (Reactmer Bond) were used in combination with a NFR composite (Metafil CX) or a FR restorative material (Reactmer Paste). Artificial caries were induced in these restorations, from which 120 +/- 10 microm thick sections and the effect of caries inhibition were quantitatively assessed with polarizing light microscopy and image analysis.
Fluid conductance after bonding with the single-step adhesives Prompt L-Pop and Etch&Prime 3.0 were not significantly different from those recorded from smear layer-covered dentin. Although better seals were achieved with One-Up Bond F and Reactmer Bond, fluid conductance at 20 cm hp was significantly higher than the two-step self-etch adhesive UniFil Bond. Osmotic conductance at 0 cm hp were not significantly different from normal fluid conductance at 20 cm hp. The sizes of artificial carious lesions in UniFil Bond were significantly higher irrespective of whether a FR or NFR composite was used. Significant reduction in lesion size occurred in Reactmer Bond with the use of a NFR composite, and even more so with the use of a FR composite.
检验以下假设，即人工诱导龋损牙本质中粘结修复体形成抑菌圈与自酸蚀粘结剂的渗透性有关。
在健康牙本质表面经过以下处理后，测量四种单步自酸蚀粘结剂（Prompt L-Pop、Etch&Prime 3.0、One-Up Bond F和Reactmer Bond）以及一种对照两步自酸蚀粘结剂（UniFil Bond）的液体传导率：（1）酸蚀；（2）抛光以形成玷污层；（3）用粘结剂粘结；每种情况均在20 cm静水压（hp）下进行。在0 cm hp下将粘结牙本质浸入4.8 M氯化钙后，还测定了其渗透液体传导率。对于人工龋抑制，将一种不含氟释放（NFR）的两步自酸蚀粘结剂（UniFil Bond）和一种含氟释放（FR）的单步粘结剂（Reactmer Bond）与一种NFR复合树脂（Metafil CX）或一种FR修复材料（Reactmer Paste）联合使用。在这些修复体中诱导人工龋，用偏光显微镜和图像分析对其中120±10微米厚的切片以及龋抑制效果进行定量评估。
用单步粘结剂Prompt L-Pop和Etch&Prime 3.0粘结后的液体传导率与覆盖玷污层的牙本质所记录的传导率无显著差异。尽管One-Up Bond F和Reactmer Bond实现了更好的封闭，但20 cm hp下的液体传导率仍显著高于两步自酸蚀粘结剂UniFil Bond。0 cm hp下的渗透传导率与20 cm hp下的正常液体传导率无显著差异。无论使用FR还是NFR复合树脂，UniFil Bond中人工龋损大小均显著更高（更大）。使用NFR复合树脂时，Reactmer Bond中的病损大小显著减小，使用FR复合树脂时减小得更多。
