Frank Y, Kurtzberg D, Kreuzer J A, Vaughan H G
Cornell University Medical College, Division of Pediatric Neurology, North Shore University Hospital, Manhasset, NY 11030.
Dev Med Child Neurol. 1992 Apr;34(4):305-15. doi: 10.1111/j.1469-8749.1992.tb11434.x.
Visual evoked potentials (VEPs) were recorded of 60 infants and children with cerebral blindness, aged between six weeks and 10 years, and compared with age-matched normative data. Every patient had abnormal VEPs. 18 had absent flash and pattern VEPs and 13 had atypical or atypical and asymmetrical flash and pattern VEPs. Of the remaining 29, most had greater abnormality of pattern than of flash VEPs and greater abnormalities over parietal and temporal than occipital areas. Eight patients had normal occipital responses to flash and five others had delayed responses with normal morphology. One had normal occipital responses to pattern stimuli. All of these had abnormal late occipital responses or abnormal responses over the parietal and temporal areas. It is recommended that visual assessments using VEPs employ both flash and pattern stimuli, that pre-occipital as well as occipital recordings be made and that tracings be compared with age-specific normative data.
对60名年龄在6周至10岁之间的脑盲婴幼儿及儿童进行了视觉诱发电位（VEP）记录，并与年龄匹配的正常数据进行比较。所有患者的VEP均异常。18例患者闪光和图形VEP缺失，13例患者闪光和图形VEP不典型或不典型且不对称。其余29例中，大多数患者图形VEP异常程度大于闪光VEP，顶叶和颞叶区域的异常程度大于枕叶区域。8例患者对闪光的枕叶反应正常，另外5例患者反应延迟但形态正常。1例患者对图形刺激的枕叶反应正常。所有这些患者枕叶晚期反应均异常或顶叶和颞叶区域反应异常。建议使用VEP进行视觉评估时同时采用闪光和图形刺激，进行枕叶前部以及枕叶记录，并将记录与特定年龄的正常数据进行比较。
