视神经脊髓炎谱系疾病的磁共振成像

MR imaging of Devic's neuromyelitis optica.

作者信息

Filippi M, Rocca M A

机构信息

Neuroimaging Research Unit, Department of Neurology, Scientific Institute and University Hospital San Raffaele Milan, Italy.

出版信息

Neurol Sci. 2004 Nov;25 Suppl 4:S371-3. doi: 10.1007/s10072-004-0344-y.

DOI:10.1007/s10072-004-0344-y

PMID:15727237

Abstract

Devic's neuromyelitis optica (NMO) is a neurological condition characterized by a severe involvement of the optic nerves and spinal cord in a mono- or multi-phasic manner. Recent pathologic, cerebrospinal fluid and conventional magnetic resonance imaging (MRI) studies have shown abnormalities which might help in differentiating patients with NMO from those with multiple sclerosis. This review article summarizes the main results obtained using conventional MRI in NMO, which has contributed to the definition of internationally-accepted diagnostic criteria, and those obtained from the application of modem quantitative MR techniques which are significantly changing our views on NMO pathobiology.

摘要

视神经脊髓炎谱系疾病（Devic's neuromyelitis optica，NMO）是一种神经系统疾病，其特征是以单相或多相方式严重累及视神经和脊髓。最近的病理学、脑脊液及传统磁共振成像（MRI）研究显示出一些异常情况，这些异常可能有助于将NMO患者与多发性硬化症患者区分开来。这篇综述文章总结了在NMO中使用传统MRI所获得的主要结果，这些结果有助于确定国际公认的诊断标准，还总结了应用现代定量MR技术所获得的结果，这些技术正在显著改变我们对NMO病理生物学的看法。