Jaais F
Department of Ophthalmology, University Malaya Medical Center, Faculty of Medicine, 50603 Kuala Lumpur, Malaysia.
Med J Malaysia. 2004 Aug;59(3):378-83.
This study reviewed the trabeculectomies (TEs) carried out in University Malaya Medical Center between 1994 to 1998. One hundred and nine of 132 eyes operated were in the primary glaucoma group of which 63 (47.7%) were of the open angle type and 46 (34.8%) were of the angle closure type. Twenty-three eyes belong to the secondary glaucoma group. Sixty-five eyes had plain or non-augmented trabeculectomy (TE) while 20 were augmented with mitomycin C (MMC) and 11 with 5 flourouracil (5FU). In 31 eyes the plain TEs were combined with extracapsular cataract extraction (ECCE) and 4 with phacoemusification. One case had combined ECCE and augmented trabeculectomy with mitomycin-C. The patients were followed up at 1 month, 6 months, 1 year and 2 years. Ninety-four of 132 (71.2%) eyes had successful surgery with intraocular pressure (IOP) of less than 21 mmHg (tonometric success) at the end of 2 years. Four of these patients needed topical medication for the IOP control. More failures were seen in patients with cystic blebs than those with diffuse blebs. Complications include hypotony, shallow anterior chamber, cataracts and hyphaema. The majority of cases (53%) had no complications.
本研究回顾了1994年至1998年间在马来亚大学医学中心进行的小梁切除术（TE）。132只接受手术的眼睛中，109只属于原发性青光眼组，其中63只（47.7%）为开角型，46只（34.8%）为闭角型。23只眼睛属于继发性青光眼组。65只眼睛进行了单纯或未增强的小梁切除术（TE），20只眼睛使用丝裂霉素C（MMC）增强，11只眼睛使用5-氟尿嘧啶（5FU）增强。31只眼睛的单纯小梁切除术与白内障囊外摘除术（ECCE）联合进行，4只眼睛与超声乳化术联合进行。1例患者进行了ECCE与丝裂霉素C增强小梁切除术联合手术。对患者进行了1个月、6个月、1年和2年的随访。132只眼睛中有94只（71.2%）在2年结束时手术成功，眼压（IOP）低于21 mmHg（眼压测量成功）。其中4名患者需要局部用药来控制眼压。与弥漫性滤泡患者相比，囊性滤泡患者的手术失败情况更多。并发症包括低眼压、前房变浅、白内障和前房积血。大多数病例（53%）没有并发症。
