van der Snoek Eric M, de Wit John B F, Mulder Paul G H, van der Meijden Willem I
Department of Dermatology and Venereology, Erasmus MC, 3015 DG Rotterdam, The Netherlands.
Sex Transm Dis. 2005 Mar;32(3):170-5. doi: 10.1097/01.olq.0000149786.09706.66.
Concerns have been expressed regarding increase in risky sex because of the availability of antiretroviral treatments in Western countries.
The goal of this longitudinal study was to investigate the association between highly active antiretroviral therapy (HAART)- and postexposure prophylaxis-related beliefs and the incidence of sexually transmitted diseases (STDs) and new HIV infections in men who have sex with men (MSM).
Data on the incidence of STDs and new HIV infection, and the level of agreement with different HAART- and PEP-related beliefs from 151 HIV-negative MSM were compiled.
Of all MSM, 65.6% tested negative for any STDs and 7 men HIV seroconverted. Perceiving less HIV/AIDS threat since HAART availability and younger age were significantly associated with a higher incidence of STDs. Perceiving less need for safe sex since HAART availability was significantly associated with an increased likelihood of HIV seroconversion.
The results support the assumption that there is an association between the incidence of STDs and a decreased perception of HIV/AIDS threat resulting from HAART availability. Less perceived need for safe sex since HAART availability was associated with HIV seroconversion.
西方国家因抗逆转录病毒治疗药物的可得性,人们对危险性行为增加表示担忧。
这项纵向研究的目标是调查高效抗逆转录病毒疗法(HAART)及暴露后预防相关观念与男男性行为者(MSM)性传播疾病(STD)发病率和新发艾滋病毒感染之间的关联。
收集了151名艾滋病毒阴性男男性行为者的性传播疾病和新发艾滋病毒感染发病率数据,以及他们对不同HAART和暴露后预防相关观念的认同程度。
在所有男男性行为者中,65.6%的人性传播疾病检测呈阴性,7名男性发生了艾滋病毒血清转化。自可获得HAART以来,认为艾滋病毒/艾滋病威胁较小以及年龄较小与性传播疾病发病率较高显著相关。自可获得HAART以来,认为安全性行为需求较少与艾滋病毒血清转化可能性增加显著相关。
结果支持以下假设,即性传播疾病发病率与因可获得HAART而导致的对艾滋病毒/艾滋病威胁认知降低之间存在关联。自可获得HAART以来,认为安全性行为需求较少与艾滋病毒血清转化有关。